Structure of PDB 4lgb Chain B Binding Site BS01

Receptor Information
>4lgb Chain B (length=292) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CIPLWGTVSIQGNRSEMEDAFAVSPHFLKLPIKMLMLTGHFFGVYDGHGG
HKVADYCRDRLHFALAEEIERIKRQVQWDKVFTSCFLTVDGEIEGKIGRA
VVDKVLEAVASETVGSTAVVALVCSSHIVVSNCGDSRAVLFRGKEAMPLS
VDHKPDREDEYARIENAGGKVIQWQGARVFGVLAMSRSIGDRYLKPYVIP
EPEVTFMPRSREDECLILASDGLWDVMNNQEVCEIARRRILMWHKKNGPL
AERGKGIDPACQAAADYLSMLALQKGSKDNISIIVIDLKAQR
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4lgb Chain B Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4lgb An ABA-mimicking ligand that reduces water loss and promotes drought resistance in plants.
Resolution3.15 Å
Binding residue
(original residue number in PDB)		D243 G244
Binding residue
(residue number reindexed from 1)		D46 G47
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.16: protein-serine/threonine phosphatase.
Gene Ontology
Molecular Function
GO:0004722 protein serine/threonine phosphatase activity
GO:0043169 cation binding
Biological Process
GO:0006470 protein dephosphorylation

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Molecular Function
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Biological Process
External links
PDB RCSB:4lgb, PDBe:4lgb, PDBj:4lgb
PDBsum4lgb
PubMed23835477
UniProtQ9CAJ0|P2C16_ARATH Protein phosphatase 2C 16 (Gene Name=HAB1)

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