Structure of PDB 4l2a Chain B Binding Site BS01

Receptor Information
>4l2a Chain B (length=192) Species: 228 (Pseudoalteromonas haloplanktis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AFELPSLPYAIDALEPHISKETLEFHHGKHHNTYVVKLNGLIPGTKFENK
SLEEIVRSSDGGVFNNAAQIWNHTFYWNSLSPNGGGAPTGAVADAINAKW
GSFDAFKEALNDKAVNNFGSSWTWLVKLADGSLDIVNTSNAATPLTDDGV
TPILTVDLWEHAYYIDYRNVRPDYLKGFWSLVNWEFANANFA
Ligand information
Ligand IDFE
InChIInChI=1S/Fe/q+3
InChIKeyVTLYFUHAOXGGBS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Fe+3]
FormulaFe
NameFE (III) ION
ChEMBL
DrugBankDB13949
ZINC
PDB chain4l2a Chain B Residue 5001 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4l2a Structural and denaturation studies of two mutants of a cold adapted superoxide dismutase point to the importance of electrostatic interactions in protein stability.
Resolution2.06 Å
Binding residue
(original residue number in PDB)		H26 H73 D157 H161
Binding residue
(residue number reindexed from 1)		H26 H73 D157 H161
Annotation score1
Enzymatic activity
Enzyme Commision number 1.15.1.1: superoxide dismutase.
Gene Ontology
Molecular Function
GO:0004784 superoxide dismutase activity
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
Biological Process
GO:0006801 superoxide metabolic process
GO:0019430 removal of superoxide radicals

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Molecular Function
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Biological Process
External links
PDB RCSB:4l2a, PDBe:4l2a, PDBj:4l2a
PDBsum4l2a
PubMed24440460
UniProtP84612|SODF_PSET1 Superoxide dismutase [Fe] (Gene Name=sodB)

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