Structure of PDB 4l0p Chain B Binding Site BS01

Receptor Information
>4l0p Chain B (length=139) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AVADRYAVYWNSSNPRFQRGDYHIDVCINDYLDVFCPHYEDSVPEDKTER
YVLYMVNFDGYSACDHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSL
GFEFRPGREYFYISSAIPDNGRRSCLKLKVFVRPTNSCM
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4l0p Chain B Residue 203 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4l0p Distinctive Structure of the EphA3/Ephrin-A5 Complex Reveals a Dual Mode of Eph Receptor Interaction for Ephrin-A5.
Resolution2.26 Å
Binding residue
(original residue number in PDB)		H49 D51
Binding residue
(residue number reindexed from 1)		H23 D25
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046875 ephrin receptor binding
Biological Process
GO:0048013 ephrin receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4l0p, PDBe:4l0p, PDBj:4l0p
PDBsum4l0p
PubMed25993310
UniProtP52803|EFNA5_HUMAN Ephrin-A5 (Gene Name=EFNA5)

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