Structure of PDB 4kv1 Chain B Binding Site BS01

Receptor Information
>4kv1 Chain B (length=126) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MNPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKL
NLPDYYKIIKTPMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKP
GDDIVLMAEALEKLFLQKINELPTEE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4kv1 Brd4 maintains constitutively active NF-kappa B in cancer cells by binding to acetylated RelA.
Resolution1.5 Å
Binding residue
(original residue number in PDB)		W81 K91 N140
Binding residue
(residue number reindexed from 1)		W39 K49 N98
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4kv1, PDBe:4kv1, PDBj:4kv1
PDBsum4kv1
PubMed23686307
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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