Structure of PDB 4kud Chain B Binding Site BS01

Receptor Information
>4kud Chain B (length=88) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKRHRKILRDNIQGITKPAIRRLARRGGVKRISGLIYEEVRAVLKSFLES
VIRDSVTYTEHAKRKTVTSLDVVYALKRQGRTLYGFGG
Ligand information
>4kud Chain I (length=146) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcaatatccacctgcagattctaccaaaagtgtatttggaaactgctcc
atcaaaaggcatgttcagcggaattccgctgaacatgccttttgatggag
cagtttccaaatacacttttggtagaatctgcaggtggatattgat
Receptor-Ligand Complex Structure
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PDB4kud N alpha-acetylated Sir3 stabilizes the conformation of a nucleosome-binding loop in the BAH domain.
Resolution3.203 Å
Binding residue
(original residue number in PDB)		R17 R19 P32 R36 R45
Binding residue
(residue number reindexed from 1)		R3 R5 P18 R22 R31
Binding affinityPDBbind-CN: Kd=0.04uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0042802 identical protein binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0006355 regulation of DNA-templated transcription
GO:0042790 nucleolar large rRNA transcription by RNA polymerase I
GO:0045943 positive regulation of transcription by RNA polymerase I
Cellular Component
GO:0000500 RNA polymerase I upstream activating factor complex
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome
GO:0031298 replication fork protection complex
GO:0032991 protein-containing complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4kud, PDBe:4kud, PDBj:4kud
PDBsum4kud
PubMed23934152
UniProtP02309|H4_YEAST Histone H4 (Gene Name=HHF1)

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