Structure of PDB 4knh Chain B Binding Site BS01

Receptor Information
>4knh Chain B (length=857) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDLRKLEALQALHAELVAVRQHRFEGLQVLETLLEEQTDAFKALIAKPAR
DTKDREALGKEPKIGEEEYSLNEDFVNDCLKLADELDLNEKESARILIDC
DAEGDVETQSRPLWECGVIRFHQERKYLLDCMRLILEIAADEDIDAGLQE
SFGVAAEDKIFGIPPVKKFIPRCMEAMKGVRSMLQCMADKANARNMLQQA
SLVRPLDNQETLDFSRLSLVEQHECLASILHAAVQRHHATIADFQDFIKI
LRKWDKYDHFLIHLIPVLAAYITEFGSPEGMGDLQQARRLNDFICKGGDE
DSWALPVLGAAVRAWWIAEHNGFYLDDTVQDLRGINLDEEDEQRTKQFLD
ALKEGAFDFILSVAADCKAQEWQDPSQLGARQWLQRKIPSLPSEPFPFSH
FLQHSLMVHLEGFVDATISNLPDVLRKLRTEEDEQRQLRPNHEQDMDLER
FLIIISYAYEGRPDAAMSFWEDPDSNLAGFLQWASRRASTPLVSAFCEML
RCLADNEECATAAHNFLLDEQSLTWSQIFKELEYFTTKVCSPAEIEPESA
LMLECYLRLIAKLATESEIARKRLIMDEDFNLVDTILKLSVGVIPHRLRA
CIFYVLKALMIRKTHEELDAMWRWVEAWMTNPFPGPQECMEMMFREFGTG
FEQSNAFIQLLTTLLVPPEGLNSLNDSVPFPEWLGSSIRTLGIEPYVDFV
FDVFANRTKDISDPSQLRILRLSCLDFVMVCLVTFNEDLIATNLATYVRL
HPFSRVMEWLFNEKVITSLINTIHQDPISLGSASPDSPLVVSILRAIQVM
IKALELQETYLHLVRYSAFEDGILSHLSLVVDLGKYCNLGHAELTLACLK
LLEKIST
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4knh Chain B Residue 1010 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4knh Evidence for an evolutionary relationship between the large adaptor nucleoporin Nup192 and karyopherins.
Resolution2.702 Å
Binding residue
(original residue number in PDB)		Q29 E32
Binding residue
(residue number reindexed from 1)		Q28 E31
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:4knh, PDBe:4knh, PDBj:4knh
PDBsum4knh
PubMed24505056
UniProtG0S4T0|NU192_CHATD Nucleoporin NUP192 (Gene Name=NUP192)

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