Structure of PDB 4jzv Chain B Binding Site BS01

Receptor Information
>4jzv Chain B (length=152) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MYEFKDYYQNTVQLSFDDQPFSDSPKHVWVICRFGGKWLLTEHEDRGYEF
PGGKVEPMECAEEAALREVKEETGARVKSLKYLGQYKVLGVIVKNIYFAD
IEKLEKQAFETKGPVLFHELPENLSRNKKFSFIMKDSVLPISLKKLKESG
WI
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4jzv Chain B Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4jzv Bacillus subtilis RNA deprotection enzyme RppH recognizes guanosine in the second position of its substrates.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		E68 E72 E115
Binding residue
(residue number reindexed from 1)		E68 E72 E110
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.1.55: 8-oxo-dGTP diphosphatase.
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0035539 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity
GO:0046872 metal ion binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:4jzv, PDBe:4jzv, PDBj:4jzv
PDBsum4jzv
PubMed23610407
UniProtO35013|YTKD_BACSU Putative 8-oxo-dGTP diphosphatase YtkD (Gene Name=ytkD)

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