Structure of PDB 4jop Chain B Binding Site BS01

Receptor Information
>4jop Chain B (length=87) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GPIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVG
DAILAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYV
Ligand information
Receptor-Ligand Complex Structure
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PDB4jop Stereochemical Preferences Modulate Affinity and Selectivity among Five PDZ Domains that Bind CFTR: Comparative Structural and Sequence Analyses.
Resolution1.8 Å
Binding residue
(original residue number in PDB)
G298 L299 G300 I301 S302 I303 T304 E308 H309 S316 H349 V353
Binding residue
(residue number reindexed from 1)
G15 L16 G17 I18 S19 I20 T21 E25 H26 S33 H66 V70
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005794 Golgi apparatus

View graph for
Cellular Component
External links
PDB RCSB:4jop, PDBe:4jop, PDBj:4jop
PDBsum4jop
PubMed24210758
UniProtQ9HD26|GOPC_HUMAN Golgi-associated PDZ and coiled-coil motif-containing protein (Gene Name=GOPC)

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