Structure of PDB 4je8 Chain B Binding Site BS01

Receptor Information
>4je8 Chain B (length=189) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPEIVASGDPVLHEKAREVDPGEIGSERIQKIIDDMIKVMRLAPCVGLAA
PQIGVPLRIIVLEDTKEYISYAPKEEILAQERRHFDLMVMVNPVLKERSN
KKALFFEGCESVDGFRAAVERYLEVVVTGYDRQGKRIEVNASGWQARILQ
HECDHLDGNLYVDKMVPRTFRTVDNLDLPLAEGCPKLGS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4je8 Understanding the highly efficient catalysis of prokaryotic peptide deformylases by shedding light on the determinants specifying the low activity of the human counterpart.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		V48 G49 G110 E112 R118 W146 R149 H153 E154
Binding residue
(residue number reindexed from 1)		V46 G47 G108 E110 R116 W144 R147 H151 E152
Enzymatic activity
Catalytic site (original residue number in PDB) G49 Q54 C111 E112 H153 E154 H157
Catalytic site (residue number reindexed from 1) G47 Q52 C109 E110 H151 E152 H155
Enzyme Commision number 3.5.1.88: peptide deformylase.
Gene Ontology
Molecular Function
GO:0042586 peptide deformylase activity

View graph for
Molecular Function
External links
PDB RCSB:4je8, PDBe:4je8, PDBj:4je8
PDBsum4je8
PubMed24531459
UniProtQ9FV53|DEF1A_ARATH Peptide deformylase 1A, chloroplastic/mitochondrial (Gene Name=PDF1A)

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