Structure of PDB 4j2j Chain B Binding Site BS01
Receptor Information
>4j2j Chain B (length=118) Species:
9606
(Homo sapiens) [
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PTLPPYFMKGSMIQLANGELKKVEDLKTEDFIQSAEMSNDLKIDSSTVER
IEDSHVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFD
LPCSKLSVGDVCISLTLK
Ligand information
>4j2j Chain E (length=17) Species:
9606
(Homo sapiens) [
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PRSVAVFPWHSLVPFLA
Receptor-Ligand Complex Structure
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PDB
4j2j
Structural basis of protein complex formation and reconfiguration by polyglutamine disease protein Ataxin-1 and Capicua
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
Y574 F575 M580 I581 Q582 L583 A584 S602 L609 Y649 I684 S685 L686 T687 L688
Binding residue
(residue number reindexed from 1)
Y6 F7 M12 I13 Q14 L15 A16 S34 L41 Y78 I113 S114 L115 T116 L117
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
Biological Process
GO:0006355
regulation of DNA-templated transcription
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Molecular Function
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Biological Process
External links
PDB
RCSB:4j2j
,
PDBe:4j2j
,
PDBj:4j2j
PDBsum
4j2j
PubMed
23512657
UniProt
P54253
|ATX1_HUMAN Ataxin-1 (Gene Name=ATXN1)
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