Structure of PDB 4j26 Chain B Binding Site BS01

Receptor Information
>4j26 Chain B (length=229) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DALSPEQLVLTLLEAEPPHVLISRPSAPFTEASMMMSLTKLADKELVHMI
SWAKKIPGFVELSLFDQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDL
VLDRDEGKCVEGILEIFDMLLATTSRFRELKLQHKEYLCVKAMILLNSSM
ADSSRKLAHLLNAVTDALVWVIAKSGISSQQQSMRLANLLMLLSHVRHAS
NKGMEHLLNMKCKNVVPVYDLLLEMLNAH
Ligand information
Receptor-Ligand Complex Structure
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PDB4j26 Proline primed helix length as a modulator of the nuclear receptor-coactivator interaction
Resolution2.3 Å
Binding residue
(original residue number in PDB)		I310 K314 L324 V328 E332 D489 E493 M494
Binding residue
(residue number reindexed from 1)		I50 K54 L64 V68 E72 D220 E224 M225
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:4j26, PDBe:4j26, PDBj:4j26
PDBsum4j26
PubMed23437920
UniProtQ92731|ESR2_HUMAN Estrogen receptor beta (Gene Name=ESR2)

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