Structure of PDB 4iwc Chain B Binding Site BS01
Receptor Information
>4iwc Chain B (length=240) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILL
NSGVYTFLTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQ
LLLILSHIRHMSNKGMEHLYSMKCKPLSDLLLEMLDAHRL
Ligand information
>4iwc Chain D (length=9) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
KILHRLLQD
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
4iwc
Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Resolution
2.24 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 Q375 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 Q71 V72 E76 D229 L230 E233
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4iwc
,
PDBe:4iwc
,
PDBj:4iwc
PDBsum
4iwc
PubMed
23524984
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
[
Back to BioLiP
]
