Structure of PDB 4iw8 Chain B Binding Site BS01
Receptor Information
>4iw8 Chain B (length=233) Species:
9606
(Homo sapiens) [
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NSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRE
LVHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLL
FAPNLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIIL
LNSGVYTDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIR
HMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>4iw8 Chain D (length=10) Species:
9606
(Homo sapiens) [
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HKILHRLLQD
Receptor-Ligand Complex Structure
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PDB
4iw8
Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Resolution
2.0375 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 E380 D538 L539 E542 M543
Binding residue
(residue number reindexed from 1)
I55 K59 V73 E77 D223 L224 E227 M228
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4iw8
,
PDBe:4iw8
,
PDBj:4iw8
PDBsum
4iw8
PubMed
23524984
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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