Structure of PDB 4ivy Chain B Binding Site BS01
Receptor Information
>4ivy Chain B (length=232) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNQGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVY
TSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRH
MSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>4ivy Chain D (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
4ivy
Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Resolution
1.95 Å
Binding residue
(original residue number in PDB)
I358 K362 V376 E380 D538 L539 E542 M543
Binding residue
(residue number reindexed from 1)
I54 K58 V72 E76 D222 L223 E226 M227
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4ivy
,
PDBe:4ivy
,
PDBj:4ivy
PDBsum
4ivy
PubMed
23524984
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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