Structure of PDB 4iv2 Chain B Binding Site BS01
Receptor Information
>4iv2 Chain B (length=238) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLI
LSHIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
Ligand information
>4iv2 Chain D (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
4iv2
Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Resolution
2.14 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 E380 D538 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 V72 E76 D228 L229 E232
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4iv2
,
PDBe:4iv2
,
PDBj:4iv2
PDBsum
4iv2
PubMed
23524984
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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