Structure of PDB 4iui Chain B Binding Site BS01

Receptor Information
>4iui Chain B (length=221) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSLTADQMVSALLDAEPPILYSEYDPTRASMMGLLTNLADRELVHMINWA
KRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLD
RMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTEEKDHIHRV
LDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSM
KCKNVVPLSDLLLEMLDAHRL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4iui Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Resolution2.3 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 L379 E542 M543
Binding residue
(residue number reindexed from 1)
I47 K51 L61 V65 L68 E214 M215
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4iui, PDBe:4iui, PDBj:4iui
PDBsum4iui
PubMed23524984
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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