Structure of PDB 4iu7 Chain B Binding Site BS01
Receptor Information
>4iu7 Chain B (length=237) Species:
9606
(Homo sapiens) [
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SLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL
VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLF
APNLLLDRNKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILS
HIRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHRL
Ligand information
>4iu7 Chain D (length=9) Species:
9606
(Homo sapiens) [
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KILHRLLQD
Receptor-Ligand Complex Structure
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PDB
4iu7
Ligand binding dynamics rewire cellular signaling via Estrogen Receptor-alpha
Resolution
2.29 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 Q375 V376 L379 E380 L539 E542
Binding residue
(residue number reindexed from 1)
I54 K58 L68 Q71 V72 L75 E76 L227 E230
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:4iu7
,
PDBe:4iu7
,
PDBj:4iu7
PDBsum
4iu7
PubMed
23524984
UniProt
P03372
|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)
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