Structure of PDB 4io7 Chain B Binding Site BS01

Receptor Information
>4io7 Chain B (length=246) Species: 104782 (Adineta vaga) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSARLKGITLRIGVIESVPFTIVANVIDGRNTTKLTGYVLDLIEYLRDKM
GFVADVQLAPPNTSYTGLVLALANGDYDIAIGDITVTSARREIVAFSNSI
SDNSMRILMRKGTLIDGMDDLKNGKIPYNRIGIRIGTAGEDYYLREISGG
SRNFYPLKSRQEMYDSLLAGIIDVSFMDIGTAEYVTNNIYCNLTLVGEDF
DKSTFGIVTPKEWLYAKDLDVNILSLRETGILDNLKKKWFQTKACP
Ligand information
Ligand IDPHE
InChIInChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1
InChIKeyCOLNVLDHVKWLRT-QMMMGPOBSA-N
SMILES
SoftwareSMILES
CACTVS 3.341N[CH](Cc1ccccc1)C(O)=O
CACTVS 3.341N[C@@H](Cc1ccccc1)C(O)=O
OpenEye OEToolkits 1.5.0c1ccc(cc1)CC(C(=O)O)N
OpenEye OEToolkits 1.5.0c1ccc(cc1)C[C@@H](C(=O)O)N
ACDLabs 10.04O=C(O)C(N)Cc1ccccc1
FormulaC9 H11 N O2
NamePHENYLALANINE
ChEMBLCHEMBL301523
DrugBankDB00120
ZINCZINC000000105196
PDB chain4io7 Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4io7 Anions Mediate Ligand Binding in Adineta vaga Glutamate Receptor Ion Channels.
Resolution1.92 Å
Binding residue
(original residue number in PDB)		Y67 D85 I86 T87 R92 T139 D180
Binding residue
(residue number reindexed from 1)		Y65 D83 I84 T85 R90 T137 D178
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0015276 ligand-gated monoatomic ion channel activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:4io7, PDBe:4io7, PDBj:4io7
PDBsum4io7
PubMed23434404
UniProtE9P5T5

[Back to BioLiP]