Structure of PDB 4hx4 Chain B Binding Site BS01

Receptor Information

>4hx4 Chain B (length=128) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TPSMEDYIKQIYMLIEEKGYARVSDIAEALAVHPSSVTKMVQKLDKDEYL
IGLVLTSKGKKIGKRLVYRHELLEQFLRIIGVDEEKIYNDVEGIEHHLSW
NSIDRIGDLVQYFEEDDARKKDLKSIQK

Ligand information

InChI=1S/Mn/q+2

WAEMQWOKJMHJLA-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mn+2]
CACTVS 3.341	[Mn++]

Formula

Mn

Name

MANGANESE (II) ION

PDB chain

4hx4 Chain B Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	4hx4 Roles of the A and C Sites in the Manganese-Specific Activation of MntR.
Resolution	1.65 Å
Binding residue (original residue number in PDB)	D8 E99 E102 H103
Binding residue (residue number reindexed from 1)	D6 E92 E95 H96
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0003700	DNA-binding transcription factor activity
GO:0030145	manganese ion binding
GO:0046872	metal ion binding
GO:0046914	transition metal ion binding
GO:0046983	protein dimerization activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription
GO:0030026	intracellular manganese ion homeostasis

	Cellular Component
GO:0005737	cytoplasm

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Cellular Component

External links

PDB	RCSB:4hx4, PDBe:4hx4, PDBj:4hx4
PDBsum	4hx4
PubMed	23298157
UniProt	P54512\|MNTR_BACSU HTH-type transcriptional regulator MntR (Gene Name=mntR)

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