Structure of PDB 4gyo Chain B Binding Site BS01

Receptor Information

>4gyo Chain B (length=359) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168)

SEEVAVKLNEWYKLIRAFEADQAEALKQEIEYDLEDMEENQDLLLYFSLM
EFRHRIMLDKLMPVKPFSDMLNEIESNQQKLTGLLEYYFYYFRGMYEFKQ
KNFILAIDHYKHAEEKLEYVEDEIEKAEFLFKVAEVYYHIKQTYFSMNYA
SQALDIYTKYELYGRRRVQCEFIIAGNLTDVYHHEKALTHLCSALEHARQ
LEEAYMIAAAYYNVGHCKYSLGDYKEAEGYFKTAAAIFEEHNFQQAVQAV
FSLTHIYCKEGKYDKAVEAYDRGIKSAAEWEDDMYLTKFRLIHELYLGSG
DLNVLTECFDLLESRQLLADAEDLLHDTAERFNQLEHYESAAFFYRRLMN
IKKKLAEQR

Ligand information

>4gyo Chain C (length=5) Species: 1423 (Bacillus subtilis)

ERGMT

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4gyo Conformational change-induced repeat domain expansion regulates rap phosphatase quorum-sensing signal receptors.
• Resolution: 2.16 Å
• Binding residue (original residue number in PDB): E147 Y150 H151 K153 Q181 F184 I185 D192 Y217 Y224 N225 H228 F250 Q260 F263 Y297 K300 D332
• Binding residue (residue number reindexed from 1): E135 Y138 H139 K141 Q169 F172 I173 D180 Y205 Y212 N213 H216 F238 Q248 F251 Y285 K288 D320

Enzymatic activity

• Enzyme Commision number: 3.1.3.-

Gene Ontology

Molecular Function

• GO:0004721 phosphoprotein phosphatase activity
• GO:0005515 protein binding

Biological Process

• GO:0030435 sporulation resulting in formation of a cellular spore

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:4gyo, PDBe:4gyo, PDBj:4gyo
• PDBsum: 4gyo
• PubMed: 23526881
• UniProt: O34327|RAPJ_BACSU Response regulator aspartate phosphatase J (Gene Name=rapJ)