Structure of PDB 4gy5 Chain B Binding Site BS01

Receptor Information
>4gy5 Chain B (length=210) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LYKVNEYVDARDTNMGAWFEAQVVRVTRKEDVIYHVKYDDYPENGVVQMN
SRDVRARARTIIKWQDLEVGQVVMLNYNPDNPKERGFWYDAEISRKRETR
TARELYANVVLGDDSLNDCRIIFVDEVFKIERPGEGSPMVDNPMRRKSGP
SCKHCKDDVNRLCRVCACHLCGGRQDPDKQLMCDECDMAFHIYCPLSSVP
SEDEWYCPEC
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4gy5 Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein
Resolution2.956 Å
Binding residue
(original residue number in PDB)		Y188 Y191 E193 N194 C316 D328 Q330 M332 P353 E355 D356
Binding residue
(residue number reindexed from 1)		Y38 Y41 E43 N44 C166 D178 Q180 M182 P200 E202 D203
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
External links
PDB RCSB:4gy5, PDBe:4gy5, PDBj:4gy5
PDBsum4gy5
PubMed23161542
UniProtQ96T88|UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1 (Gene Name=UHRF1)

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