Structure of PDB 4gct Chain B Binding Site BS01

Receptor Information
>4gct Chain B (length=189) Species: 243277 (Vibrio cholerae O1 biovar El Tor str. N16961) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NRREEILQALAEMLESNEGASRITTAKLAKQVGVSEAALYRHFPSKTRMF
EGLIEFIEESLMSRINRIFDEEKDTLNRIRLVMQLLLAFAERNPGLTRIL
SGHALMFENERLRDRINQLFERIETSLRQILRERKLREGKSFPVDENILA
AQLLGQVEGSLNRFVRSDFKYLPTANFDEYWALLSAQIK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4gct SlmA forms a higher-order structure on DNA that inhibits cytokinetic Z-ring formation over the nucleoid.
Resolution2.45 Å
Binding residue
(original residue number in PDB)		R29 T31 T32 E43 Y47 S52 K53
Binding residue
(residue number reindexed from 1)		R22 T24 T25 E36 Y40 S45 K46
Binding affinityPDBbind-CN: Kd=53.4nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0010974 negative regulation of division septum assembly
GO:0051301 cell division
GO:0051302 regulation of cell division
Cellular Component
GO:0005737 cytoplasm
GO:0009295 nucleoid
GO:0043590 bacterial nucleoid

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4gct, PDBe:4gct, PDBj:4gct
PDBsum4gct
PubMed23754405
UniProtQ9KVD2|SLMA_VIBCH Nucleoid occlusion factor SlmA (Gene Name=slmA)

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