Structure of PDB 4fsj Chain B Binding Site BS01

Receptor Information
>4fsj Chain B (length=309) Species: 12287 (Flock House virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ALTRLSQPGLAFLKCAFAPPDFNTDPGKGIPDRFEGKVVSRKDVLNQSIS
FTAGQDTFILIAPTPGVAYWSASVPAGTFPTSATTFNPVNYPGFTSMFGT
TSTSRSDQVSSFRYASMNVGIYPTSNLMQFAGSITVWKCPVKLSTVQFPV
ATDPATSSLVHTLVGLDGVLAVGPDNFSESFIKGVFSQSACNEPDFEFND
ILEGIQTLPPANVSLGSTGQPFTMDSGAEATSGVVGWGNMDTIVIRVSAP
EGAVNSAILKAWSCIEYRPNPNAMLYQFGHDSPPLDEVALQEYRTVARSL
PVAVIAAQN
Ligand information
>4fsj Chain E (length=17) Species: 12287 (Flock House virus) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ASMWERVKSIIKSSLAA
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4fsj Structural study of virus assembly intermediates reveals maturation event sequence and a staging position for externalized lytic peptides
Resolution3.5 Å
Binding residue
(original residue number in PDB)
A55 L56 K68 F71 A72 E346 V350 S353 Q362 N363
Binding residue
(residue number reindexed from 1)
A1 L2 K14 F17 A18 E292 V296 S299 Q308 N309
Enzymatic activity
Enzyme Commision number 3.4.23.44: nodavirus endopeptidase.
Gene Ontology
Molecular Function
GO:0004190 aspartic-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:4fsj, PDBe:4fsj, PDBj:4fsj
PDBsum4fsj
PubMed
UniProtP12870|CAPSD_FHV Capsid protein alpha (Gene Name=alpha)

[Back to BioLiP]