Structure of PDB 4fqx Chain B Binding Site BS01

Receptor Information

>4fqx Chain B (length=187) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VLFQGPGDTRPRFLWQLKFECHFFNGTERVRLLERSIYNQEESVRFDSDV
GEYRAVTELGRPDAEYWNSQKDLLEQRRAAVDTYCRHNYGVGESFTVQRR
VEPKVTVYPSLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGLIQNGDW
TFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRA

Ligand information

>4fqx Chain E (length=7) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

NCLKLAT

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4fqx Crystal Structure of the HLA-DM-HLA-DR1 Complex Defines Mechanisms for Rapid Peptide Selection.
Resolution	2.599 Å
Binding residue (original residue number in PDB)	D57 W61
Binding residue (residue number reindexed from 1)	D63 W67

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0006955	immune response
GO:0019882	antigen processing and presentation

	Cellular Component
GO:0016020	membrane
GO:0042613	MHC class II protein complex

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Biological Process

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Cellular Component

External links

PDB	RCSB:4fqx, PDBe:4fqx, PDBj:4fqx
PDBsum	4fqx
PubMed	23260142
UniProt	P01911\|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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