Structure of PDB 4fpv Chain B Binding Site BS01

Receptor Information
>4fpv Chain B (length=257) Species: 7955 (Danio rerio) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TAKSEVEDSKLSIISWNVDGLDTLNLADRARGLCSYLALYTPDVVFLQEL
IPAYVQYLKKRAVSYLFFEGSDDGYFTGIMLRKSRVKFLESEIICFPTTQ
MMRNLLIAQVTFSGQKLYLMTSHLESCKNQSQERTKQLRVVLQKIKEAPE
DAIVIFAGDTNLRDAEVANVGGLPAGVCDVWEQLGKQEHCRYTWDTKANS
NKTVPYVSRCRFDRIFLRSAKTAPPVTPDHMALIGMEKLDCGRYTSDHWG
IYCTFNT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4fpv Structural basis for recognition of 5'-phosphotyrosine adducts by Tdp2.
Resolution1.73 Å
Binding residue
(original residue number in PDB)
K240 N241 Q244
Binding residue
(residue number reindexed from 1)
K128 N129 Q132
Enzymatic activity
Enzyme Commision number 3.1.4.-
Gene Ontology
Molecular Function
GO:0003824 catalytic activity

View graph for
Molecular Function
External links
PDB RCSB:4fpv, PDBe:4fpv, PDBj:4fpv
PDBsum4fpv
PubMed23104058
UniProtQ5XJA0|TYDP2_DANRE Tyrosyl-DNA phosphodiesterase 2 (Gene Name=tdp2)

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