Structure of PDB 4fln Chain B Binding Site BS01

Receptor Information
>4fln Chain B (length=464) Species: 3702 (Arabidopsis thaliana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HDASFLNAVVKVYCTHTAPDYSLPWQKQRQFTSTGSAFMIGDGKLLTNAH
CVEHDTQVKVKRRGDDRKYVAKVLVRGVDCDIALLSVESEDFWKGAEPLR
LGHLPRLQDSVTVVGYPLGGDTISVTKGVVSRIEVTSYAHGSSDLLGIQI
DAAINPGNSGGPAFNDQGECIGVAFQVYTENIGYVIPTTVVSHFLTDYER
NGKYTGYPCLGVLLQKLENPALRECLKVPTNEGVLVRRVEPTSDASKVLK
EGDVIVSFDDLHVGCEGTVPFRSSERIAFRYLISQKFAGDIAEIGIIRAG
EHKKVQVVLRPRVHLVPYHIDGGQPSYIIVAGLVFTPLSEPLIEEECEDT
IGLKLLTKARYSVARFRGEQIVILSQVLANEVNIGYEDMNNQQVLKFNGI
PIRNIHHLAHLIDMCKDKYLVFEFEDNYVAVLEREASNSASLCILKDYGI
PSERSADLLEPYVD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4fln Crystal structure of Arabidopsis deg2 protein reveals an internal PDZ ligand locking the hexameric resting state.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		S252 D253 Y320 P321 C322 L323 V325 L326 L327 R393 I396 S397 R425 R473 Y474 V476
Binding residue
(residue number reindexed from 1)		S143 D144 Y207 P208 C209 L210 V212 L213 L214 R280 I283 S284 R312 R360 Y361 V363
Enzymatic activity
Enzyme Commision number 3.4.21.-
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4fln, PDBe:4fln, PDBj:4fln
PDBsum4fln
PubMed22961982
UniProtO82261|DEGP2_ARATH Protease Do-like 2, chloroplastic (Gene Name=DEGP2)

[Back to BioLiP]