Structure of PDB 4fgn Chain B Binding Site BS01
Receptor Information
>4fgn Chain B (length=124) [
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DPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTF
ISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMY
SALTRDPFSVIEESLPGGLKEHDF
Ligand information
>4fgn Chain Z (length=23) [
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aggcctccaaaaaagcctcctca
Receptor-Ligand Complex Structure
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PDB
4fgn
Analysis of the Costructure of the Simian Virus 40 T-Antigen Origin Binding Domain with Site I Reveals a Correlation between GAGGC Spacing and Spiral Assembly.
Resolution
3.2 Å
Binding residue
(original residue number in PDB)
N153 R202 H203 R204 A207 N210
Binding residue
(residue number reindexed from 1)
N20 R69 H70 R71 A74 N77
Binding affinity
PDBbind-CN
: Kd~12.3nM
Enzymatic activity
Enzyme Commision number
3.6.4.-
Gene Ontology
Molecular Function
GO:0003688
DNA replication origin binding
Biological Process
GO:0006260
DNA replication
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Molecular Function
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Biological Process
External links
PDB
RCSB:4fgn
,
PDBe:4fgn
,
PDBj:4fgn
PDBsum
4fgn
PubMed
23269808
UniProt
P03070
|LT_SV40 Large T antigen
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