Structure of PDB 4fcm Chain B Binding Site BS01

Receptor Information
>4fcm Chain B (length=135) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVMEKPSPLLVGREFVRQYYTLLNQAPDMLHRFYGKNSSYVHGGLDKPAD
AVYGQKEIHRKVMSQNFTNCHTKIRHVDAHATLNDGVVVQVMGLLSNNNQ
ALRRFMQTFVLAPEGSVANKFYVHNDIFRYQDEVF
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4fcm Crystal Structures of the Human G3BP1 NTF2-Like Domain Visualize FxFG Nup Repeat Specificity.
Resolution2.69 Å
Binding residue
(original residue number in PDB)
P6 V11 E14 F15 Q18 R32 F33 E117 K123 F124 Y125
Binding residue
(residue number reindexed from 1)
P6 V11 E14 F15 Q18 R32 F33 E114 K120 F121 Y122
Enzymatic activity
Enzyme Commision number 3.6.4.12: DNA helicase.
3.6.4.13: RNA helicase.
External links
PDB RCSB:4fcm, PDBe:4fcm, PDBj:4fcm
PDBsum4fcm
PubMed24324649
UniProtQ13283|G3BP1_HUMAN Ras GTPase-activating protein-binding protein 1 (Gene Name=G3BP1)

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