Structure of PDB 4f99 Chain B Binding Site BS01

Receptor Information
>4f99 Chain B (length=90) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RLKKPFVKVEDMSQLYRPFYLQLTNMPFINYSIQKPCSPFDGYCECCLQK
YEDLETHLLSEQHRNFAQSNQYQVVDDIVSKLVFDFVEYE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4f99 Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4f99 Crystal structure of human CDC7 kinase in complex with its activator DBF4.
Resolution2.33 Å
Binding residue
(original residue number in PDB)		C296 C299 H309 H315
Binding residue
(residue number reindexed from 1)		C44 C47 H57 H63
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:4f99, PDBe:4f99, PDBj:4f99
PDBsum4f99
PubMed23064647
UniProtQ9UBU7|DBF4A_HUMAN Protein DBF4 homolog A (Gene Name=DBF4)

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