Structure of PDB 4f4z Chain B Binding Site BS01

Receptor Information
>4f4z Chain B (length=341) Species: 273057,330779 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIVLFVDFDYFYAQVEEVLNPSLKGKPVVVCVFSGRFEDSGAVATANYEA
RKFGVKAGIPIVEAKKILPNAVYLPMRKEVYQQVSSRIMNLLREYSEKIE
IASIDEAYLDISDKVRDYREAYNLGLEIKNKILEKEKITVTVGISKNKVF
AKIAADMAKPNGIKVIDDEEVKRLIRELDIADVPGIGNITAEKLKKLGIN
KLVDTLSIEFDKLKGMIGEAKAKYLISLARDEYNEPIRTRVRKSIGRYLT
LPYNTRDVKVILPYLKKAINEAYNKVNGIPMRITVIAIMEDLDILSKGKK
FKHGISIDNAYKVAEDLLRELLVRDKRRNVRRIGVKLDNII
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4f4z Y-family polymerase conformation is a major determinant of fidelity and translesion specificity.
Resolution2.305 Å
Binding residue
(original residue number in PDB)
A57 G58 G185 I186 G187 I189 T190 K297 K300 R324
Binding residue
(residue number reindexed from 1)
A57 G58 G185 I186 G187 I189 T190 K297 K300 R324
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0003684 damaged DNA binding
GO:0003887 DNA-directed DNA polymerase activity
Biological Process
GO:0006281 DNA repair

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:4f4z, PDBe:4f4z, PDBj:4f4z
PDBsum4f4z
PubMed23245850
UniProtQ4JB80|DPO4_SULAC DNA polymerase IV (Gene Name=dbh);
Q97W02|DPO4_SACS2 DNA polymerase IV (Gene Name=dbh)

[Back to BioLiP]