Structure of PDB 4dsj Chain B Binding Site BS01

Receptor Information
>4dsj Chain B (length=575) Species: 1422 (Geobacillus stearothermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KMAFTLADRVTEEMLADKAALVVEVVEENYHDAPIVGIAVVNEHGRFFLR
PETALADPQFVAWLGDETKKKSMFDSKRAAVALKWKGIELCGVSFDLLLA
AYLLDPAQGVDDVAAAAKMKQYEAVRPDEAVYGKGAKRAVPDEPVLAEHL
VRKAAAIWELERPFLDELRRNEQDRLLVELEQPLSSILAEMEFAGVKVDT
KRLEQMGKELAEQLGTVEQRIYELAGQEFNINSPKQLGVILFEKLQLPVL
KGYSTSADVLEKLAPYHEIVENILHYRQLGKLQSTYIEGLLKVVRPDTKK
VHTIFNQALTQTGRLSSTEPNLQNIPIRLEEGRKIRQAFVPSESDWLIFA
ADYSQIELRVLAHIAEDDNLMEAFRRDLDIHTKTAMDIFQVSEDEVTPNM
RRQAKAVNFGIVYGISDYGLAQNLNISRKEAAEFIERYFESFPGVKRYME
NIVQEAKQKGYVTTLLHRRRYLPDITSRNFNVRSFAERMAMNTPIQGSAA
DIIKKAMIDLNARLKEERLQAHLLLQVHDELILEAPKEEMERLCRLVPEV
MEQAVTLRVPLKVDYHYGSTWYDAK
Ligand information
Receptor-Ligand Complex Structure
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PDB4dsj Biochemical and structural insights into the fidelity of bacillus stearothermophilus DNA polymerase
Resolution2.86 Å
Binding residue
(original residue number in PDB)		K431 A433 T556 A558 R578 K582 Y587 R615 Q624 N625 I626 P627 I628 R629 H829 D830
Binding residue
(residue number reindexed from 1)		K134 A136 T255 A257 R277 K281 Y286 R314 Q323 N324 I325 P326 I327 R328 H528 D529
Enzymatic activity
Enzyme Commision number 2.7.7.7: DNA-directed DNA polymerase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004518 nuclease activity
GO:0008408 3'-5' exonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006260 DNA replication
GO:0006261 DNA-templated DNA replication
GO:0006281 DNA repair
GO:0006302 double-strand break repair
GO:0006974 DNA damage response
GO:0071897 DNA biosynthetic process

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Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4dsj, PDBe:4dsj, PDBj:4dsj
PDBsum4dsj
PubMed
UniProtE1C9K5

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