Structure of PDB 4day Chain B Binding Site BS01
Receptor Information
>4day Chain B (length=113) Species:
9606
(Homo sapiens) [
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AGVRLPRSPPLKVLAEQLRRDAAVWMQGRVVMADRGEARLRDPSGDFSVR
GLERVPRGRPCLVPGKYVMVMGVVQACSPEPCLQAVKMTDLSDNPIHESM
WELEVEDLHRNIP
Ligand information
>4day Chain C (length=12) Species:
9606
(Homo sapiens) [
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DLFSVTFDLGFC
Receptor-Ligand Complex Structure
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PDB
4day
Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome.
Resolution
3.3 Å
Binding residue
(original residue number in PDB)
V15 R16 L17 P18 V120 K121
Binding residue
(residue number reindexed from 1)
V3 R4 L5 P6 V86 K87
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0005515
protein binding
Biological Process
GO:0000724
double-strand break repair via homologous recombination
GO:0006260
DNA replication
GO:0006281
DNA repair
GO:0033045
regulation of sister chromatid segregation
GO:0043007
maintenance of rDNA
GO:0071139
resolution of DNA recombination intermediates
GO:2000042
negative regulation of double-strand break repair via homologous recombination
Cellular Component
GO:0005634
nucleus
GO:0005654
nucleoplasm
GO:0005829
cytosol
GO:0016607
nuclear speck
GO:0031422
RecQ family helicase-topoisomerase III complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:4day
,
PDBe:4day
,
PDBj:4day
PDBsum
4day
PubMed
22392978
UniProt
Q96E14
|RMI2_HUMAN RecQ-mediated genome instability protein 2 (Gene Name=RMI2)
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