Structure of PDB 4cns Chain B Binding Site BS01

Receptor Information

>4cns Chain B (length=477) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MTSDRLLIKGGRIVNDDQSFYADIYMEDGLIKQIGDNLIVPGGVKTIEAN
GKMVIPGGIDVHTHYQMPYKGMTTVDDFFQGTKAALAGGTTMIIDHVVPE
PESSLTEAYEKWREWADGKSCCDYALHVDITHWNDSVKQEVQNLIKDKGV
NSFMVYMAYKDLYQVSNTELYEIFTCLGELGAIAQVHAENGDIIAQEQTR
MLEMGITGPEGHVLSRPEELEAEAVFRAITIASQTNCPLYVTKVMSKSAA
DLISQARKKGNVVFGEPITASLGIDGTHYWSKNWAKAAAFVTSPPLSPDP
TTPDYINSLLASGDLQLSGSAHCTFSTAQKAIGKDNFTAIPEGTNGVEER
MSVIWDKAVATGKMDENQFVAVTSTNAAKIFNLYPRKGRISVGSDSDLVI
WDPDAVKIVSAKNHQSAAEYNIFEGMELRGAPLVVICQGKIMLEDGNLHV
TQGAGRFIPCSPFSDYVYKRIKARRKM

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

4cns Chain B Residue 1490 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	4cns Crystal Structure of Human Crmp-4: Correction of Intensities for Lattice-Translocation Disorder
Resolution	2.4 Å
Binding residue (original residue number in PDB)	D128 G464 G466
Binding residue (residue number reindexed from 1)	D117 G453 G455
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0016787	hydrolase activity
GO:0016810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds

	Cellular Component
GO:0005737	cytoplasm

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Molecular Function

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Cellular Component

External links

PDB	RCSB:4cns, PDBe:4cns, PDBj:4cns
PDBsum	4cns
PubMed	24914979
UniProt	Q14195\|DPYL3_HUMAN Dihydropyrimidinase-related protein 3 (Gene Name=DPYSL3)

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