Structure of PDB 4clv Chain B Binding Site BS01

Receptor Information
>4clv Chain B (length=142) Species: 119219 (Cupriavidus metallidurans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SRTFRLSVSTLVGALVGVLMAIVGVYVTHSTEEPHTSLHEMLHDAVPLDS
NEREILELKEEEFTARRREIESRLRAANGKLAESIAKNPQWSPEVEEATR
EVERAAADLQRATLVHVFEMRAGLKPEHRAAYDRVLVDALKR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4clv Chain B Residue 1146 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4clv The X-Ray Structure of Nccx from Cupriavidus Metallidurans 31A Illustrates Potential Dangers of Detergent Solubilization When Generating and Interpreting Crystal Structures of Membrane Proteins.
Resolution3.12 Å
Binding residue
(original residue number in PDB)		H38 E63 H119
Binding residue
(residue number reindexed from 1)		H35 E60 H116
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0046686 response to cadmium ion

View graph for
Biological Process
External links
PDB RCSB:4clv, PDBe:4clv, PDBj:4clv
PDBsum4clv
PubMed25258316
UniProtQ44582|NCCX_ALCXX Nickel-cobalt-cadmium resistance protein NccX (Gene Name=nccX)

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