Structure of PDB 4cei Chain B Binding Site BS01

Receptor Information
>4cei Chain B (length=1152) Species: 224308 (Bacillus subtilis subsp. subtilis str. 168) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GAEFLVGRSGSGKTKLIINSIQDELRRAPFGKPIIFLVPDQMTFLMEYEL
AKTPDMGGMIRAQVFSFSRLAWRVLQHTGGMSRPFLTSTGVQMLLRKLIE
EHKQEFKVYQKASDKSGFTAQVERMLTEFKRYCLEPEDIRRMSEYRGERV
LSEKLHDLSILYQQMEKSLADQYLHSEDYLTLLAEHIPLAEDIKGAHIYV
DGFYQFTPQEFRVLEQLMVHAEHITFSLTADKPSYEREPHELELFRMTGK
TYYRLHQKAKELNLDITYKELSGTERHTKTPELAHLEAQYEARPAIPYAE
KQEALTVMQAANRRAELEGIAREIHALVREKGYRYKDVAILARQPEDYKD
MVKEVFADYEIPYFIDGKASMLNHPLIEFIRSSLDVLKGNWRYEAVFRCV
KTELLFPLNEPKAKVREQVDQLENYCIAYGIKGDRWTKGDRFQYRRFVSL
DDDFAQTDQEIEMENMLNDTRDWIVPPLFQLQKRMKKAKTVQEKAEALYR
YLEETDVPLKLDQERQRAEDDGRIIEAQQHQQAWDAVIQLLEEFVEMMGD
DEISLDLFQQMIEAGAESLTFSLIPPALDQVFVGNMDLSRMYGTSCTFVL
GANDGVLPARPDENGVLSDDDREWLKTIGVELSSGGRERLLDEHFLIYMA
FSSPSDRLYVSYPIADAEGKTLLPSMIVKRLEELFPHHKERLLTNEPEQV
SDEEQLMYVVNKSVAQSFTASQLRLWTREYDISDVWWSTYNVLMSEQDRL
QSKKLFSSLFFRNEVKQLERSVSRQLYGERIQGSVSRMETFNACPFSHFA
SHGLHLKERQFFKLEAPDIGQLFHSSLKLISDRLRDEKLDWRDLTKEQCE
LFSYDAVERLAPKLQKEILLSSNRHYYVKEKLQKIVTRVSGILSEHAKAS
GFVPIGLELGFGGKGPLPPLTFQLKNGCTMELVGRIDRVDKAESSKGLLL
RIVAYKSSDKGLDLAEVYYGLALQMLTYLDLSITHSADWLGMRATPAGVL
YFHIHDPMIQSNLPLGLDEIEQEIFKKFKMKGLLLGDQEVVRLMDTTLQE
GRSNIINAGLKKDGSLRSDSAAVGEKEFDLLTKHVRRTFQEAGEQITDGR
VSIEPYKMKNKTPCTYCAFKSVCQFDESLEENEYRPLKAEKDKTILEWIK
KE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4cei Structural Basis for Translocation by Addab Helicase-Nuclease and its Arrest at Chi Sites.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		R1059 K1068 K1069 R1074 S1075
Binding residue
(residue number reindexed from 1)		R1052 K1061 K1062 R1067 S1068
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008409 5'-3' exonuclease activity
GO:0016787 hydrolase activity
GO:0016788 hydrolase activity, acting on ester bonds
GO:0046872 metal ion binding
GO:0051536 iron-sulfur cluster binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0000724 double-strand break repair via homologous recombination
GO:0006281 DNA repair
GO:0006310 DNA recombination

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:4cei, PDBe:4cei, PDBj:4cei
PDBsum4cei
PubMed24670664
UniProtP23477|ADDB_BACSU ATP-dependent helicase/deoxyribonuclease subunit B (Gene Name=addB)

[Back to BioLiP]