Structure of PDB 4am7 Chain B Binding Site BS01

Receptor Information
>4am7 Chain B (length=623) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EIDLNDPTATIVIHPGSNSIKIGFPKDDHPVVVPNCVAVPKKWLDLENSE
HVENVCLQREQSEEFNNIKSEMEKNFRERMRYYKRKVPGNAHEQVVSFNE
NSKPEIISEKNDPSPIEWIFDDSKLYYGSDALRCVDEKFVIRKPFRGGSF
NVKSPYYKSLAELISDVTKLLEHALNSETLNVKPTKFNQYKVVLVIPDIF
KKSHVETFIRVLLTELQFQAVAIIQESLATCYGAGISTSTCVVNIGAAET
RIACVDEGTVLEHSAITLDYGGDDITRLFALFLLQSDFPLQDWKIDSKHG
WLLAERLKKNFTTFQDADVAVQLYNFMNRSPNQPTEKYEFKLFDEVMLAP
LALFFPQIFKLIRTSSHKNSSLEFQLPESRDLFTNELNDWNSLSQFESKE
GNLYCDLNDDLKILNRILDAHNIIDQLQDKPENYGNTLKENFAPLEKAIV
QSIANASITADVTRMNSFYSNILIVGGSSKIPALDFILTDRINIWRPSLL
SSASFPQFYKKLTKEIKDLEGHYVNAPDKTEDENKQILQAQIKEKIVEEL
EEQHQNIEHQNGNEHIFPVSIIPPPRDMNPALIIWKGASVLAQIKLVEEL
FITNSDWDVHGSRILQYKCIFTY
Ligand information
Ligand IDADP
InChIInChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKeyXTWYTFMLZFPYCI-KQYNXXCUSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[CH]3O[CH](CO[P](O)(=O)O[P](O)(O)=O)[CH](O)[CH]3O
ACDLabs 10.04O=P(O)(O)OP(=O)(O)OCC3OC(n2cnc1c(ncnc12)N)C(O)C3O
CACTVS 3.341Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO[P@@](O)(=O)O[P](O)(O)=O)[C@@H](O)[C@H]3O
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)O)O)N
FormulaC10 H15 N5 O10 P2
NameADENOSINE-5'-DIPHOSPHATE
ChEMBLCHEMBL14830
DrugBankDB16833
ZINCZINC000012360703
PDB chain4am7 Chain B Residue 1882 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4am7 Interactions between the Nucleosome Histone Core and Arp8 in the Ino80 Chromatin Remodeling Complex.
Resolution3.25 Å
Binding residue
(original residue number in PDB)		G274 S275 N276 G504 A505 E563 K566 K567 G735 S736
Binding residue
(residue number reindexed from 1)		G16 S17 N18 G246 A247 E305 K308 K309 G477 S478
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4am7, PDBe:4am7, PDBj:4am7
PDBsum4am7
PubMed23213201
UniProtQ12386|ARP8_YEAST Actin-like protein ARP8 (Gene Name=ARP8)

[Back to BioLiP]