Structure of PDB 4al2 Chain B Binding Site BS01

Receptor Information
>4al2 Chain B (length=167) Species: 469008 (Escherichia coli BL21(DE3)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEGIGLAATQ
VDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALV
PRAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLK
QQRIRQKVEKLDRLKAR
Ligand information
Ligand IDH2S
InChIInChI=1S/H2S/h1H2
InChIKeyRWSOTUBLDIXVET-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S
FormulaH2 S
NameHYDROSULFURIC ACID;
HYDROGEN SULFIDE
ChEMBLCHEMBL1200739
DrugBank
ZINC
PDB chain4al2 Chain B Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4al2 A Fret Enzyme-Based Probe for Monitoring Hydrogen Sulfide.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		Q50 C90 L91
Binding residue
(residue number reindexed from 1)		Q50 C90 L91
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) G45 Q50 C90 L91 H132 E133 H136
Catalytic site (residue number reindexed from 1) G45 Q50 C90 L91 H132 E133 H136
Enzyme Commision number 3.5.1.88: peptide deformylase.
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0008198 ferrous iron binding
GO:0008270 zinc ion binding
GO:0016787 hydrolase activity
GO:0042586 peptide deformylase activity
GO:0043022 ribosome binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0043686 co-translational protein modification
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4al2, PDBe:4al2, PDBj:4al2
PDBsum4al2
PubMed23072298
UniProtP0A6K3|DEF_ECOLI Peptide deformylase (Gene Name=def)

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