Structure of PDB 4air Chain B Binding Site BS01

Receptor Information
>4air Chain B (length=304) Species: 5664 (Leishmania major) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PFDKSRNVAQSIDQLIGQTPALYLNKLNNTKAKVVLKMECENPMASVKDR
LGFAIYDKAEKEGKLIPGKSVVVESSSGNTGVSLAHLGAIRGYKVIITMP
ESMSLERRCLLRIFGAEVILTPAALGMKGAVTMAKKIVTANPNAVLADQF
ATKYNALIHEETTGPEIWEQTNHNVDCFIAGVGTGGTLTGVARALKKMGS
HARIVAVEPMEDRSLIDEVFCVAGDDAIETALKLTRSDGVFCGFSGGANV
YAALKIAERPEMEGKTIVTIIPSFGERYLSTALYRSVRDEVSSLPVVDAS
ELQD
Ligand information
Receptor-Ligand Complex Structure
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PDB4air Structure of Leishmania Major Cysteine Synthase.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		K51 S79 S80 G81 N82 T83 R110 M130 G272 F273 S274 Y307
Binding residue
(residue number reindexed from 1)		K48 S76 S77 G78 N79 T80 R107 M127 G243 F244 S245 Y278
Enzymatic activity
Catalytic site (original residue number in PDB) K51 S274
Catalytic site (residue number reindexed from 1) K48 S245
Enzyme Commision number 2.5.1.47: cysteine synthase.
Gene Ontology
Molecular Function
GO:0004124 cysteine synthase activity
GO:0016740 transferase activity
Biological Process
GO:0006535 cysteine biosynthetic process from serine
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4air, PDBe:4air, PDBj:4air
PDBsum4air
PubMed22750854
UniProtQ4Q159

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