Structure of PDB 4a37 Chain B Binding Site BS01

Receptor Information
>4a37 Chain B (length=376) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AMQIRADFDSGNIQVIDASDPRRIRLAIRPDLASQHFQWFHFKVEGMAPA
TEHCFTLVNAGQSAYSHAWSGYQAVASYDGERWFRVPSQYDADGLHFQLE
PEESEVRFAYFEPYSRERHARLVERALGIEGVERLAVGTSVQGRDIELLR
VRRHPDSHLKLWVIAQQHPGEHMAEWFMEGLIERLQRPDDTEMQRLLEKA
DLYLVPNMNPDGAFHGNLRTNAAGQDLNRAWLEPSAERSPEVWFVQQEMK
RHGVDLFLDIHGDEEIPHVFAAGCEGNPGYTPRLERLEQRFREELMARGE
FQIRHGYPRSAPGQANLALACNFVGQTYDCLAFTIEMPFKDHDDNPEPGT
GWSGARSKRLGQDVLSTLAVLVDELR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4a37 Chain B Residue 753 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4a37 The Novel Structure of a Cytosolic M14 Metallocarboxypeptidase (Ccp) from Pseudomonas Aeruginosa: A Model for Mammalian Ccps.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		H167 E170 H260
Binding residue
(residue number reindexed from 1)		H168 E171 H261
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004181 metallocarboxypeptidase activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:4a37, PDBe:4a37, PDBj:4a37
PDBsum4a37
PubMed22645247
UniProtQ9I012

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