Structure of PDB 3zrq Chain B Binding Site BS01

Receptor Information
>3zrq Chain B (length=382) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DKLLLHVGPTTIKEDVLVAGLENNVGFTSKEFVEALAYSLKGLRYVMGAS
KNYQPLIIPGGGTSAMESVTSLLKPNDKILVVSNGVFGDRWEQIFKRYPV
NVKVLRPSPGDYVKPGEVEEEVRKSEYKLVALTHVETSTGVREPVKDVIN
KIRKYVELIVVDGVSSVGAEEVKAEEWNVDVYLTASQKALGSAAGLGLLL
LSPKALSILDSQNSIAGYYLDLRNWLPVMRGAEEGKAAYFATPPVHVILQ
LAEAFRLIEKEGIENRIKRHTMVASAIRAGLEALGLEIVARRPESYSNTV
TGVILKVADPQKVLAGTVNEGVEFAPGVHPAFKYFRIGHMGWVTPNDAII
AISVIERTLRKLGEPIRFGEGVKAVEEVLFSA
Ligand information
Ligand IDPMP
InChIInChI=1S/C8H13N2O5P/c1-5-8(11)7(2-9)6(3-10-5)4-15-16(12,13)14/h3,11H,2,4,9H2,1H3,(H2,12,13,14)
InChIKeyZMJGSOSNSPKHNH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=P(O)(O)OCc1cnc(c(O)c1CN)C
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)CN)O
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(CN)c1O
FormulaC8 H13 N2 O5 P
Name4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE;
PYRIDOXAMINE-5'-PHOSPHATE
ChEMBLCHEMBL1235353
DrugBankDB02142
ZINCZINC000001532708
PDB chain3zrq Chain A Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3zrq Crystal Structure and Substrate Specificity of the Thermophilic Serine:Pyruvate Aminotransferase from Sulfolobus Solfataricus
Resolution1.8 Å
Binding residue
(original residue number in PDB)		Y240 T243
Binding residue
(residue number reindexed from 1)		Y239 T242
Annotation score1
Enzymatic activity
Enzyme Commision number 2.6.1.51: serine--pyruvate transaminase.
Gene Ontology
Molecular Function
GO:0004760 L-serine-pyruvate transaminase activity
GO:0008453 alanine-glyoxylate transaminase activity
GO:0008483 transaminase activity
GO:0046872 metal ion binding
Biological Process
GO:0019265 glycine biosynthetic process, by transamination of glyoxylate
Cellular Component
GO:0005777 peroxisome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3zrq, PDBe:3zrq, PDBj:3zrq
PDBsum3zrq
PubMed22751661
UniProtQ97VM5

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