Structure of PDB 3zid Chain B Binding Site BS01

Receptor Information
>3zid Chain B (length=342) Species: 2224 (Methanothrix thermoacetophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLNVLMLGVGQCGNRILDAVNRQAFSRVETIAINTAINDLKELKFTAAKD
RLHVPNGVGANRSKGKQGFWENQEMILEEIEKRGDFDLIFVMTSVSGGTG
SSFSPLMIHELKKRYKNATIVPIAVLPFREEGTIYLQNAAFCLREMIEVE
ADGMILVDNQYLKRIASAYDRINTMVAQRLLFLIEALDSETDLGDFKTVM
NGGLRMGTLGYYQADKKSPSIRAAIKNSLREVGLLYPANVDAGEAGRAMI
VIQGSREYLNVDEITKEIESLTETIGHVFKGIVIKKGEPRVLSVLSLERA
PGLVELYEKAKWAIQEERERKDRARSELYEAFEQINDLEEIY
Ligand information
Ligand IDGDP
InChIInChI=1S/C10H15N5O11P2/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChIKeyQGWNDRXFNXRZMB-UUOKFMHZSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6c1nc2c(n1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N
CACTVS 3.385NC1=Nc2n(cnc2C(=O)N1)[C@@H]3O[C@H](CO[P](O)(=O)O[P](O)(O)=O)[C@@H](O)[C@H]3O
CACTVS 3.385NC1=Nc2n(cnc2C(=O)N1)[CH]3O[CH](CO[P](O)(=O)O[P](O)(O)=O)[CH](O)[CH]3O
ACDLabs 12.01O=P(O)(O)OP(=O)(O)OCC3OC(n2cnc1c2N=C(N)NC1=O)C(O)C3O
OpenEye OEToolkits 1.7.6c1nc2c(n1[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N
FormulaC10 H15 N5 O11 P2
NameGUANOSINE-5'-DIPHOSPHATE
ChEMBLCHEMBL384759
DrugBankDB04315
ZINCZINC000008215481
PDB chain3zid Chain B Residue 999 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3zid Cetz Tubulin-Like Proteins Control Archaeal Cell Shape
Resolution2.0 Å
Binding residue
(original residue number in PDB)		G10 Q11 C12 R15 S111 G114 T116 G117 F145 E148 N176 Y190 N194
Binding residue
(residue number reindexed from 1)		G10 Q11 C12 R15 S94 G97 T99 G100 F128 E131 N159 Y169 N173
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0008360 regulation of cell shape
GO:0051301 cell division
Cellular Component
GO:0005737 cytoplasm
GO:0032153 cell division site

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3zid, PDBe:3zid, PDBj:3zid
PDBsum3zid
PubMed25533961
UniProtA0B5R2|CETZ_METTP Tubulin-like protein CetZ (Gene Name=cetZ)

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