Structure of PDB 3zfk Chain B Binding Site BS01

Receptor Information
>3zfk Chain B (length=128) Species: 469008 (Escherichia coli BL21(DE3)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPEFPGKATGKGKPVNNKWLNNAGKDLGSPVPDRIANKLRDKEFKSFDDF
RKKFWEEVSKDPELSKQFSRNNNDRMKVGKAPKTRTQDVSGKRTSFELHH
EKPISQNGGVYDMDNISVVTPKRHIDIH
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3zfk Chain B Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3zfk A New Insight Into the Zinc-Dependent DNA-Cleavage by the Colicin E7 Nuclease: A Crystallographic and Computational Study.
Resolution1.7 Å
Binding residue
(original residue number in PDB)		H544 H569 H573
Binding residue
(residue number reindexed from 1)		H99 H124 H128
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) R538 E542 H544 H545 H569 H573
Catalytic site (residue number reindexed from 1) R93 E97 H99 H100 H124 H128
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0005102 signaling receptor binding
Biological Process
GO:0009617 response to bacterium
GO:0019835 cytolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3zfk, PDBe:3zfk, PDBj:3zfk
PDBsum3zfk
PubMed25179124
UniProtQ47112|CEA7_ECOLX Colicin-E7 (Gene Name=colE7)

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