Structure of PDB 3zeu Chain B Binding Site BS01

Receptor Information
>3zeu Chain B (length=337) Species: 909946 (Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRVLGIETSCDETGIAIYDDKKGLLANQLYSQVKLHADYGGVVPELASRD
HVRKTVPLIQAALKEAGLTASDIDAVAYTAGPGLVGALLVGATVGRSLAF
AWNVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQ
YELLGESIDDAAGEAFDKTAKLLGLDYPGGPMLSKMASQGTAGRFVFPRP
MTDRPGLDFSFSGLKTFAANTIRSNGGDEQTRADIARAFEDAVVDTLMIK
CKRALESTGFKRLVMAGGVSANRTLRAKLAEMMQKRRGEVFYARPEFCTD
NGAMIAYAGMVRFKAGVTADLGVTVRPRWPLAELPAA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain3zeu Chain B Residue 1339 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3zeu Crystal Structure of the Dimer of Two Essential Salmonella Typhimurium Proteins, Ygjd & Yeaz and Calorimetric Evidence for the Formation of a Ternary Ygjd-Yeaz-Yjee Complex.
Resolution1.653 Å
Binding residue
(original residue number in PDB)		H111 H115 D300
Binding residue
(residue number reindexed from 1)		H111 H115 D300
Annotation score1
Enzymatic activity
Enzyme Commision number 2.3.1.234: N(6)-L-threonylcarbamoyladenine synthase.
Gene Ontology
Molecular Function
GO:0005506 iron ion binding
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0046872 metal ion binding
GO:0061711 N(6)-L-threonylcarbamoyladenine synthase activity
Biological Process
GO:0002949 tRNA threonylcarbamoyladenosine modification
GO:0006400 tRNA modification
GO:0008033 tRNA processing
GO:0070525 tRNA threonylcarbamoyladenosine metabolic process
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3zeu, PDBe:3zeu, PDBj:3zeu
PDBsum3zeu
PubMed23471679
UniProtP40731|TSAD_SALTY tRNA N6-adenosine threonylcarbamoyltransferase (Gene Name=tsaD)

[Back to BioLiP]