Structure of PDB 3wqz Chain B Binding Site BS01

Receptor Information
>3wqz Chain B (length=904) Species: 224325 (Archaeoglobus fulgidus DSM 4304) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTLDEEYLDITFLTENGFVRKRCPKCGKHFWTADPEREICGDPPCESYSF
IGNPVFKKPFELDEMREYYLNFFERRGHGRIERYPVVARWRTDIYLTIAS
IADFQPFVTSGVAPPPANPLTISQPCIRLDDLDSVGRTGRHLTLFEMMAH
HAFNYPGKEIYWKNETVAYCTELLNELGVKKEDIVYKEEPWAGGGNAGPC
LEAIVGGLEVATLVFMNLEEHPEGDIEIKGARYRKMDNYIVDTGYGLERF
VWASKGTPTVYDAIFPEVVDTIIDNSNVSFNREDERVRRIVAESSKLAGI
MGELRGERLNQLRKSVADTVGVSVEELEGIVVPLEKVYSLADHTRCILFM
LGDGLVPSNAGAGYLARLMIRRSLRLAEELELGLDLYDLVEMHKKILGFE
FDVPLSTVQEILELEKERYRTTVSKGTRLVERLVERKKKLEKDDLIELYD
SHGIPVELAVGIAAEKGAEVEMPKDIYAELAKRHSKAEKVQEKKITLQNE
YPATEKLYYDDPTLLEFEAEVIGVEGDFVILNRSAFYPESGGQDNDVGYL
IANGGKFEVVDVLEADGVVLHVVKGAKPEVGTKVKGVIDSDVRWRHMRHH
SATHVLLYSLQKVLGNHVWQAGARKEFSKARLDVTHFRRPSEEEIKEIEM
LANREILANKPIKWEWMDRIEAERKFGFRLYQGGVPPGRKIRVVQVGDDV
QACGGTHCRSTGEIGMLKILKVESIQDGVIRFEFAAGEAAIEAVEEMERL
LREASSILRVEPAKLPKTVERFFEEWKDQRKEIERLKSVIADLWADILME
RAEEFDSMKVVAEVVDADMQALQKLAERLAEKGAVGCLMAKGEGKVFVVT
FSGQKYDARELLREIGRVAKGSGGGRKDVAQGAVQQLLDREEMLDVIFRF
LSEH
Ligand information
>3wqz Chain C (length=75) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggacucguagcucagcgggagagcgccgccuuugcgaggcggaggccgcg
gguucaaaucccgccgaguccacca
<<<<<<<..<<<<.......>>>>.<<<<<<<...>>>>>>>.....<<<
<<.......>>>>>>>>>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB3wqz The selective tRNA aminoacylation mechanism based on a single G.U pair
Resolution3.489 Å
Binding residue
(original residue number in PDB)		L758 F772
Binding residue
(residue number reindexed from 1)		L758 F772
Enzymatic activity
Enzyme Commision number 6.1.1.7: alanine--tRNA ligase.
Gene Ontology
Molecular Function
GO:0000049 tRNA binding
GO:0000166 nucleotide binding
GO:0002161 aminoacyl-tRNA editing activity
GO:0003676 nucleic acid binding
GO:0004812 aminoacyl-tRNA ligase activity
GO:0004813 alanine-tRNA ligase activity
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006412 translation
GO:0006419 alanyl-tRNA aminoacylation
GO:0043039 tRNA aminoacylation
GO:0106074 aminoacyl-tRNA metabolism involved in translational fidelity
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:3wqz, PDBe:3wqz, PDBj:3wqz
PDBsum3wqz
PubMed24919148
UniProtO28029|SYA_ARCFU Alanine--tRNA ligase (Gene Name=alaS)

[Back to BioLiP]