Structure of PDB 3wng Chain B Binding Site BS01

Receptor Information
>3wng Chain B (length=136) Species: 11698 (Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLA
GRWPVKTVHTDNGSNFTGATVRAACDWAGIKQESMNKELKKIIGQVRDQA
EHLKTAVQMAVFIHNHKRKGYSAGERIVDIIATDIQ
Ligand information
Receptor-Ligand Complex Structure
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PDB3wng Hexapeptide mimetics of LEDGF in complex with HIV-1 integrase
Resolution1.75 Å
Binding residue
(original residue number in PDB)		D167 Q168 A169 E170 H171 T174
Binding residue
(residue number reindexed from 1)		D98 Q99 A100 E101 H102 T105
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:3wng, PDBe:3wng, PDBj:3wng
PDBsum3wng
PubMed
UniProtP12497|POL_HV1N5 Gag-Pol polyprotein (Gene Name=gag-pol)

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