Structure of PDB 3w6w Chain B Binding Site BS01

Receptor Information
>3w6w Chain B (length=555) Species: 5062 (Aspergillus oryzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPYLITGIPKDPKHPLPIRKDIDDWYLEQTSAGSNRIQLTLFVEALTVIQ
NRPLNDQLSYFRLAGIHGAPWTEWDGVPGGTGFCVHNNYTFPTWHRVYVT
LYEQVIYEAMLDFIKQNVPQNGKADWENEAKQWRLPYWDFARFARHGHDG
DELRLPILVTMPMVKVLVPGQPGKQLSKPNPLYRFQMQTLMGTLERPYAI
TFDLPFDKCQSTTKYGLLENYNADVWADGGQNWLRANLALNEHPWYQNLD
GWDSVPTLQDMTFRLLTTGGLNWGEFSSTRYDAPKNWMNLEAIHNNVHNW
VGGFMFSRPGRHDLKLWGAGHMSSVPVAAYDPIFWLHHCNIDRLTAIWQT
VNSGSWFNDDKSKVSKDDDLRPFHRFCEKTRKVVFFRSDDVKDWRSLNYD
YAITKDASRIRKEISDLYGQRTKEVYKDFGEEDYILSIRYSRYALGGKPF
QINIFFGDVDGKDFYDARSQNFVGSVFNFSVLSVSQLPARLAVHYYKKQN
KGEVPTPRYVVVNSQGKAEAEVKVEVALHKTEGTFYDYRRVADGKRAEVD
DAYRA
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain3w6w Chain B Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3w6w Crystal structures of copper-depleted and copper-bound fungal pro-tyrosinase: insights into endogenous cysteine-dependent copper incorporation.
Resolution1.394 Å
Binding residue
(original residue number in PDB)		H67 H94 H103
Binding residue
(residue number reindexed from 1)		H67 H86 H95
Annotation score1
Enzymatic activity
Enzyme Commision number 1.14.18.1: tyrosinase.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Cellular Component
External links
PDB RCSB:3w6w, PDBe:3w6w, PDBj:3w6w
PDBsum3w6w
PubMed23749993
UniProtQ2UP46

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