Structure of PDB 3vpp Chain B Binding Site BS01

Receptor Information
>3vpp Chain B (length=122) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SPCPNNWIQNRESCYYVSEIWSIWHTSQENCLKEGSTLLQIESKEEMDFI
TGSLRKIKGSYDYWVGLSQDGHSGRWLWQDGSSPSPGLLPAENQVCGYVK
SNSLLSSNCDTWKYFICEKYAL
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain3vpp Chain B Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3vpp The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments.
Resolution1.642 Å
Binding residue
(original residue number in PDB)		Q150 E152 E156 E233
Binding residue
(residue number reindexed from 1)		Q40 E42 E46 E118
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006898 receptor-mediated endocytosis
Cellular Component
GO:0016020 membrane

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Biological Process
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Cellular Component
External links
PDB RCSB:3vpp, PDBe:3vpp, PDBj:3vpp
PDBsum3vpp
PubMed22483802
UniProtQ6UXN8|CLC9A_HUMAN C-type lectin domain family 9 member A (Gene Name=CLEC9A)

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