Structure of PDB 3v11 Chain B Binding Site BS01

Receptor Information
>3v11 Chain B (length=254) Species: 273057 (Saccharolobus solfataricus P2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MIYSRSKLPSEGEILIATVKQVFDYGSYVSLDEYGGLQAFLPWSEVSNIR
DVLKENRKVIVKVIRVDRRKGTVDVSLKKVTDDERRKKNLQWKKIQRLDK
ILELVSQKLKLSEKDAWEQVAWKLEAKYGDPITAIEKAVKEGEKILIDAG
VPEIWVKPLLEEASRKVKMSGLITVRTNEPLGVEKIKEVISKALENIEQD
YESLLNIKIYTIGAPRYRVDVVGTNPKEASEALNQIISNLIKIGKEENVD
ISVV
Ligand information
>3v11 Chain D (length=76) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gcgggguggagcagccugguagcucgucgggcucauaacccgaagaucgu
cgguucaaauccggcccccgcaacca
<<<<<<..<<<<.........>>>>.<<<<<.......>>>>>......<
<<<.......>>>>.>>>>>>.....
Receptor-Ligand Complex Structure
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PDB3v11 Structure of the ternary initiation complex aIF2-GDPNP-methionylated initiator tRNA.
Resolution5.0 Å
Binding residue
(original residue number in PDB)		N53 R62 N94 W97 Q101 K105
Binding residue
(residue number reindexed from 1)		N48 R57 N89 W92 Q96 K100
Binding affinityPDBbind-CN: Kd=1nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
GO:0043022 ribosome binding
Biological Process
GO:0006412 translation
GO:0006413 translational initiation

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Molecular Function
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Biological Process
External links
PDB RCSB:3v11, PDBe:3v11, PDBj:3v11
PDBsum3v11
PubMed22447243
UniProtQ97Z79|IF2A_SACS2 Translation initiation factor 2 subunit alpha (Gene Name=eif2a)

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