Structure of PDB 3uo8 Chain B Binding Site BS01

Receptor Information
>3uo8 Chain B (length=364) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MLAKDKVALLIGNMNYREHPKLKAPLVDVYELTNLLRQLDFKVVSLLDLT
EYEMRNAVDEFLLLLDKGVYGLLYYAGHGYENFGNSFMVPVDAPNPYRSE
NCLCVQNILKLMQEKETGLNVFLLDMCRKRNDYDDTIPILDALKVTANIV
FGYATCQGAEAFEIQHSGLANGIFMKFLKDRLLEDKKITVLLDEVAEDMG
KCHLTKGKQALEIRSSLSEKRALTDPIQWAKAHELPESMCLKFDCGVQIQ
LGFAAEFSNVMIIYTSIVYKPPEIIMCDAYVTDFPLDLDIDPKDANKGTP
EETGSYLVSKDLPKHCLYTRLSSLQKLKEHLVFTVCLSYQYSGLEDTVED
KQEVNVGKPLIAKL
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3uo8 Crystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase region.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		L359 A361 P362 D365 G414 H415 D462 C464 A498 F499 E500 I501 Q502
Binding residue
(residue number reindexed from 1)		L22 A24 P25 D28 G77 H78 D125 C127 A161 F162 E163 I164 Q165
Enzymatic activity
Enzyme Commision number 3.4.22.-
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:3uo8, PDBe:3uo8, PDBj:3uo8
PDBsum3uo8
PubMed22158899
UniProtQ9UDY8|MALT1_HUMAN Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Gene Name=MALT1)

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