Structure of PDB 3uhf Chain B Binding Site BS01

Receptor Information
>3uhf Chain B (length=249) Species: 192222 (Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AMKIGVFDSGVGGLSVLKSLYEARLFDEIIYYGDTARVPYGVKDKDTIIK
FCLEALDFFEQFQIDMLIIACNTASAYALDALRAKAHFPVYGVIDAGVEA
TIKALHDKNKEILVIATKATIKSEEYQKRLLSQGYTNINALATGLFVPMV
EEGIFEGDFLQSAMEYYFKNITTPDALILACTHFPLLGRSLSKYFGDKTK
LIHSGDAIVEFLKERENIDLKNHKAKLHFYASSDVESLKNTAKIWLNLL
Ligand information
Ligand IDDGL
InChIInChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m1/s1
InChIKeyWHUUTDBJXJRKMK-GSVOUGTGSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0C(CC(=O)O)[C@H](C(=O)O)N
ACDLabs 12.01O=C(O)C(N)CCC(=O)O
OpenEye OEToolkits 1.7.0C(CC(=O)O)C(C(=O)O)N
CACTVS 3.370N[C@H](CCC(O)=O)C(O)=O
CACTVS 3.370N[CH](CCC(O)=O)C(O)=O
FormulaC5 H9 N O4
NameD-GLUTAMIC ACID
ChEMBLCHEMBL76232
DrugBankDB02517
ZINCZINC000000895124
PDB chain3uhf Chain B Residue 260 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB3uhf Crystal Structure of Glutamate Racemase from Campylobacter jejuni subsp. jejuni
Resolution1.83 Å
Binding residue
(original residue number in PDB)		S8 P38 Y39 G40 C70 N71 T72 C180 T181 H182
Binding residue
(residue number reindexed from 1)		S9 P39 Y40 G41 C71 N72 T73 C181 T182 H183
Annotation score5
Enzymatic activity
Catalytic site (original residue number in PDB) D7 S8 C70 E150 C180 H182
Catalytic site (residue number reindexed from 1) D8 S9 C71 E151 C181 H183
Enzyme Commision number 5.1.1.3: glutamate racemase.
Gene Ontology
Molecular Function
GO:0008881 glutamate racemase activity
GO:0016853 isomerase activity
GO:0016855 racemase and epimerase activity, acting on amino acids and derivatives
GO:0036361 racemase activity, acting on amino acids and derivatives
Biological Process
GO:0008360 regulation of cell shape
GO:0009252 peptidoglycan biosynthetic process
GO:0071555 cell wall organization

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:3uhf, PDBe:3uhf, PDBj:3uhf
PDBsum3uhf
PubMed
UniProtQ9PM24|MURI_CAMJE Glutamate racemase (Gene Name=murI)

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